Journal article
Randomized Trial of Behavioral Activation, Cognitive Therapy, and Antidepressant Medication in the Acute Treatment of Adults With Major Depression
Journal of consulting and clinical psychology, Vol.74(4), pp.658-670
08/2006
Handle:
https://hdl.handle.net/2376/108058
PMID: 16881773
Abstract
Antidepressant medication is considered the current standard for severe depression, and cognitive therapy is the most widely investigated psychosocial treatment for depression. However, not all patients want to take medication, and cognitive therapy has not demonstrated consistent efficacy across trials. Moreover, dismantling designs have suggested that behavioral components may account for the efficacy of cognitive therapy. The present study tested the efficacy of behavioral activation by comparing it with cognitive therapy and antidepressant medication in a randomized placebo-controlled design in adults with major depressive disorder (
N =
241). In addition, it examined the importance of initial severity as a moderator of treatment outcome. Among more severely depressed patients, behavioral activation was comparable to antidepressant medication, and both significantly outperformed cognitive therapy. The implications of these findings for the evaluation of current treatment guidelines and dissemination are discussed.
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Details
- Title
- Randomized Trial of Behavioral Activation, Cognitive Therapy, and Antidepressant Medication in the Acute Treatment of Adults With Major Depression
- Creators
- Sona Dimidjian - Department of Psychology, University of WashingtonSteven D Hollon - Department of Psychology, Vanderbilt UniversityKeith S Dobson - Department of Psychology, University of Calgary, Calgary, Alberta, CanadaKaren B Schmaling - College of Health and Human Services, University of North Carolina at CharlotteRobert J Kohlenberg - Department of Psychology, University of WashingtonMichael E Addis - Department of Psychology, Clark UniversityRobert Gallop - Department of Mathematics and Applied Statistics, West Chester UniversityJoseph B McGlinchey - Department of Psychiatry and Human Behavior, Brown UniversityDavid K Markley - Department of Psychology, University of WashingtonJackie K Gollan - Department of Psychiatry, University of ChicagoDavid C Atkins - Travis Research Institute, Fuller Graduate School of PsychologyDavid L Dunner - Department of Psychiatry and Behavioral Sciences, University of WashingtonNeil S Jacobson - Department of Psychology, University of Washington
- Publication Details
- Journal of consulting and clinical psychology, Vol.74(4), pp.658-670
- Academic Unit
- Psychology, Department of
- Publisher
- American Psychological Association
- Identifiers
- 99900546718901842
- Language
- English
- Resource Type
- Journal article