Response to “Why all randomized controlled trials produce biased results”

Andrew D Althouse; Kaleab Z Abebe; Gary S Collins; Frank E Harrell

doi:10.1080/07853890.2018.1514529

Back

Response to “Why all randomized controlled trials produce biased results”

Journal article

Open access

Peer reviewed

Response to “Why all randomized controlled trials produce biased results”

Andrew D Althouse, Kaleab Z Abebe, Gary S Collins and Frank E Harrell

Annals of medicine (Helsinki), Vol.50(7), pp.545-548

10/03/2018

DOI: https://doi.org/10.1080/07853890.2018.1514529

Handle:

https://hdl.handle.net/2376/112826

PMID: 30122065

Files and links (1)

url

https://doi.org/10.1080/07853890.2018.1514529View

Published (Version of record) Open

Abstract

In April 2018, the Annals of Medicine published a provocative piece titled “Why all randomized controlled trials produce biased results” [Citation1]. While the strengths and limitations of RCTs remain a fertile discussion topic, the piece in question leaves much to be desired. In many places, the piece ignores prior literature that explains and/or refutes several key points. Absent a formal response, this piece may create confusion to understanding of RCTs in the research community.

Metrics

15 Record Views

See more details

Details

Title: Response to “Why all randomized controlled trials produce biased results”
Creators: Andrew D Althouse - University of Pittsburgh School of Medicine, 200 Meyran Avenue, Suite 300, Pittsburgh, PA 15213, USA
Kaleab Z Abebe - University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Gary S Collins - Centre for Statistics in Medicine, University of Oxford, Oxford, United Kingdom
Frank E Harrell - Department of Biostatistics, Vanderbilt University, Nashville, TN, USA
Publication Details: Annals of medicine (Helsinki), Vol.50(7), pp.545-548
Academic Unit: Department of Physics and Astronomy
Identifiers: 99900547937301842
Language: English
Resource Type: Journal article