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Rickettsia felis infection in febrile patients, western Kenya, 2007-2010
Journal article   Open access  Peer reviewed

Rickettsia felis infection in febrile patients, western Kenya, 2007-2010

Alice N Maina, Darryn L Knobel, Ju Jiang, Jo Halliday, Daniel R Feikin, Sarah Cleaveland, Zipporah Ng'ang'a, Muthoni Junghae, Robert F Breiman, Allen L Richards, …
Emerging infectious diseases, Vol.18(2), pp.328-331
02/2012
DOI: https://doi.org/10.3201/eid1802.111372
Handle:
https://hdl.handle.net/2376/107145
PMCID: PMC3310467
PMID: 22304807
url
https://doi.org/10.3201/eid1802.111372View
Published (Version of record) Open

Abstract

Kenya - epidemiology Rickettsia Infections - immunology Fever - microbiology Humans Middle Aged Child, Preschool Infant Male Seroepidemiologic Studies Fever - epidemiology Case-Control Studies Molecular Typing Incidence Rickettsia felis - genetics Young Adult Fever - blood Adult Female Fever - immunology Antibodies, Bacterial - blood Child Rickettsia Infections - epidemiology Rickettsia felis - isolation & purification Rickettsia Infections - microbiology Bacterial Proteins - genetics Sequence Analysis, DNA Adolescent Rickettsia Infections - blood
To determine previous exposure and incidence of rickettsial infections in western Kenya during 2007-2010, we conducted hospital-based surveillance. Antibodies against rickettsiae were detected in 57.4% of previously collected serum samples. In a 2008-2010 prospective study, Rickettsia felis DNA was 2.2× more likely to be detected in febrile than in afebrile persons.

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