Journal article
Risk factors for head and neck cancer in young adults: a pooled analysis in the INHANCE consortium
International journal of epidemiology, Vol.44(1), pp.169-185
02/2015
Handle:
https://hdl.handle.net/2376/114280
PMCID: PMC4339764
PMID: 25613428
Abstract
Increasing incidence of head and neck cancer (HNC) in young adults has been reported. We aimed to compare the role of major risk factors and family history of cancer in HNC in young adults and older patients.
We pooled data from 25 case-control studies and conducted separate analyses for adults ≤ 45 years old ('young adults', 2010 cases and 4042 controls) and >45 years old ('older adults', 17700 cases and 22 704 controls). Using logistic regression with studies treated as random effects, we estimated adjusted odds ratios (ORs) and 95% confidence intervals (CIs).
The young group of cases had a higher proportion of oral tongue cancer (16.0% in women; 11.0% in men) and unspecified oral cavity / oropharynx cancer (16.2%; 11.1%) and a lower proportion of larynx cancer (12.1%; 16.6%) than older adult cases. The proportions of never smokers or never drinkers among female cases were higher than among male cases in both age groups. Positive associations with HNC and duration or pack-years of smoking and drinking were similar across age groups. However, the attributable fractions (AFs) for smoking and drinking were lower in young when compared with older adults (AFs for smoking in young women, older women, young men and older men, respectively, = 19.9% (95% CI=9.8%, 27.9%), 48.9% (46.6%, 50.8%), 46.2% (38.5%, 52.5%), 64.3% (62.2%, 66.4%); AFs for drinking=5.3% (-11.2%, 18.0%), 20.0% (14.5%, 25.0%), 21.5% (5.0%, 34.9%) and 50.4% (46.1%, 54.3%). A family history of early-onset cancer was associated with HNC risk in the young [OR=2.27 (95% CI=1.26, 4.10)], but not in the older adults [OR=1.10 (0.91, 1.31)]. The attributable fraction for family history of early-onset cancer was 23.2% (8.60% to 31.4%) in young compared with 2.20% (-2.41%, 5.80%) in older adults.
Differences in HNC aetiology according to age group may exist. The lower AF of cigarette smoking and alcohol drinking in young adults may be due to the reduced length of exposure due to the lower age. Other characteristics, such as those that are inherited, may play a more important role in HNC in young adults compared with older adults.
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- Title
- Risk factors for head and neck cancer in young adults: a pooled analysis in the INHANCE consortium
- Creators
- Tatiana Natasha Toporcov - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PrePhilip Lazarus - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreAriana Znaor - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreZuo-Feng Zhang - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreGuo-Pei Yu - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreDeborah M Winn - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreQingyi Wei - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreMarta Vilensky - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreThomas Vaughan - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PrePeter Thomson - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreRenato Talamini - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreNeonila Szeszenia-Dabrowska - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreErich M Sturgis - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreElaine Smith - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreOxana Shangina - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreStephen M Schwartz - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreStimson Schantz - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PrePeter Rudnai - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreLorenzo Richiardi - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreHeribert Ramroth - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreMark P Purdue - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreAndrew F Olshan - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreJosé Eluf-Neto - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreJoshua Muscat - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreRaquel Ajub Moyses - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreHal Morgenstern - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreAna Menezes - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreMichael McClean - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreKeitaro Matsuo - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreDana Mates - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreTatiana V Macfarlane - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreJolanta Lissowska - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreFabio Levi - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreCarlo La Vecchia - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PrePagona Lagiou - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreSergio Koifman - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreKristina Kjaerheim - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreKarl Kelsey - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreIvana Holcatova - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreRolando Herrero - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreClaire Healy - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreRichard B Hayes - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreSilvia Franceschi - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreLeticia Fernandez - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreEleonora Fabianova - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreAlexander W Daudt - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreOtávio Alberto Curioni - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreLuigino Dal Maso - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreMaria Paula Curado - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreDavid I Conway - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreChu Chen - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreXavier Castellsague - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreCristina Canova - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreGabriella Cadoni - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PrePaul Brennan - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreStefania Boccia - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreJosé Leopoldo Ferreira Antunes - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreWolfgang Ahrens - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreAntonio Agudo - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PrePaolo Boffetta - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreMia Hashibe - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreYuan-Chin Amy Lee - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and PreVictor Wünsch Filho - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil, Croatian National Cancer Registry, Zagreb, Croatia, UCLA School of Public Health, Los Angeles, CA, USA, Medical Informatics Center, Peking University, Beijing, China, and New York Medical College, Valhalla, NY, USA, National Cancer Institute, Bethesda, MD, USA, UT-MD Anderson Cancer Center, Houston, TX, USA, Institute of Oncology Angel H. Roffo, University of Buenos Aires, Buenos Aires, Argentina, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, School of Dental Sciences, University of Newcastle, Newcastle, UK, Aviano Cancer Centre, Aviano, Italy, Institute of Occupational Medicine, Lodz, Poland, College of Public Health, University of Iowa, Iowa City, IA, USA, Cancer Research Centre, Moscow, Russia, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, New York Eye and Ear Infirmary, New York, NY, USA, National Institute of Environmental Health, Budapest, Hungary, Department of Medical Science, Cancer Epidemiology Unit, University of Turin, Turin, Italy, Institute of Public Health, University of Heidelberg, Heidelberg, Germany, University of North Carolina School of Public Health, Chapel Hill, NC, USA, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Penn State College of Medicine, Hershey, PA, USA, Cirurgia de Cabeça e Pescoço (LIM 28), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Comprehensive Cancer Center, University of Michigan Ann Arbor, Ann Arbor, MI, USA, Universidade Federal de Pelotas, Pelotas, Brazil, Boston University School of Public Health, Boston, MA, USA, Aichi Cancer Center Research Institute, Nagoya, Japan, Institute of Public Health, Bucharest, Romania, University of Aberdeen Dental School, Aberdeen, UK, The M Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Cancer Epidemiology and Pre
- Publication Details
- International journal of epidemiology, Vol.44(1), pp.169-185
- Academic Unit
- Department of Pharmaceutical Sciences
- Publisher
- England
- Grant note
- R03CA77954 / NCI NIH HHS T32 CA009142 / NCI NIH HHS R01CA30022 / NCI NIH HHS R01CA048996 / NCI NIH HHS R01DE11979 / NIDCR NIH HHS R03CA113157 / NCI NIH HHS R01CA51845 / NCI NIH HHS R01DE13110 / NIDCR NIH HHS R21ES011667 / NIEHS NIH HHS P30 ES010126 / NIEHS NIH HHS R01ES11740 / NIEHS NIH HHS R01DA11386 / NIDA NIH HHS P50CA90388 / NCI NIH HHS R01DE012609 / NIDCR NIH HHS R03DE016611 / NIDCR NIH HHS P30ES010126 / NIEHS NIH HHS U01CA96134 / NCI NIH HHS T32CA09142 / NCI NIH HHS 001 / World Health Organization P01CA068384 / NCI NIH HHS K07CA104231 / NCI NIH HHS FIRCA TW01500 / FIC NIH HHS R01CA61188 / NCI NIH HHS R01DE13158 / NIDCR NIH HHS R01CA100264 / NCI NIH HHS
- Identifiers
- 99900547403601842
- Language
- English
- Resource Type
- Journal article