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S-(2-Pyridinyl)-1,1,3,3-Tetramethylthiouronium Hexafluorophosphate. A New Reagent for the Synthesis of 2-Pyridinethiol Esters
Journal article   Peer reviewed

S-(2-Pyridinyl)-1,1,3,3-Tetramethylthiouronium Hexafluorophosphate. A New Reagent for the Synthesis of 2-Pyridinethiol Esters

Noemi Scardovi, Philip P Garner and John D Protasiewicz
Organic letters, Vol.5(10), pp.1633-1635
05/15/2003
Handle:
https://hdl.handle.net/2376/109551
PMID: 12735739

Abstract

A new thiouronium-based reagent for the synthesis of 2-pyridinethiol esters under non-nucleophilic conditions from the corresponding carboxylic acids was developed. The resulting procedure enables the preparation of previously unavailable α,β-unsaturated 2-pyridinethiol esters as well as their aliphatic and aromatic counterparts.

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