Journal article
S-Nitrosothiols: chemistry and reactions
Chemical communications (Cambridge, England), Vol.53(82), pp.11266-11277
2017
Handle:
https://hdl.handle.net/2376/108579
PMID: 28944382
Abstract
The formation of S-nitrosothiols (SNO) in protein cysteine residues is an important post-translational modification elicited by nitric oxide (NO). This process is involved in virtually every class of cell signaling and has attracted considerable attention in redox biology. On the other hand, their unique structural characters make SNO potentially useful synthons. In this review, we summarized the fundamental chemical/physical properties of SNO. We also highlighted the reported chemical reactions of SNO, including the reactions with phosphine reagents, sulfinic acids, various nucleophiles, SNO-mediated radical additions, and the reactions of acyl SNO species.
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Details
- Title
- S-Nitrosothiols: chemistry and reactions
- Creators
- Caihong Zhang - School of Chemistry and Chemical Engineering, Institute of Environmental Science Shanxi University, Taiyuan, China, Department of ChemistryTyler D Biggs - Department of Chemistry, Washington State University, Pullman, USANelmi O Devarie-Baez - Department of Chemistry, Washington State University Tri-Cities, Richland, USAShaomin Shuang - School of Chemistry and Chemical Engineering, Institute of Environmental Science Shanxi University, Taiyuan, ChinaChuan Dong - School of Chemistry and Chemical Engineering, Institute of Environmental Science Shanxi University, Taiyuan, ChinaMing Xian - School of Chemistry and Chemical Engineering, Institute of Environmental Science Shanxi University, Taiyuan, China, Department of Chemistry
- Publication Details
- Chemical communications (Cambridge, England), Vol.53(82), pp.11266-11277
- Academic Unit
- Biological Systems Engineering, Department of; Chemistry, Department of
- Identifiers
- 99900546990501842
- Language
- English
- Resource Type
- Journal article