Journal article
Seawater adaptability and hormone levels in growth-enhanced transgenic coho salmon, Oncorhynchus kisutch
Aquaculture, Vol.191(4), pp.367-385
2000
Handle:
https://hdl.handle.net/2376/116956
Abstract
Transgenic coho salmon containing a growth hormone (GH) gene construct have been examined for their hormone levels and ability to osmoregulate in sea water. Relative to their smaller nontransgenic siblings (age controls), GH-transgenic coho precociously develop external phenotypes and hypo-osmoregulatory ability typical of smolts. Specific growth rates of the transgenic coho were approximately 2.7-fold higher than older nontransgenic animals of similar size, and 1.7-fold higher than their nontransgenic siblings. GH levels were increased dramatically (19.3- to 32.1-fold) relative to size control salmon, but IGF-I levels were only modestly affected, being slightly enhanced in one experiment and slightly reduced in another. Insulin levels in transgenic animals did not differ from size controls, but were higher than nontransgenic siblings, and thyroxine levels in transgenic animals were intermediate between levels found in size and age controls. The homeostatic controls of, and interactions among, these hormones are discussed with respect to their effects on growth and osmoregulation.
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Details
- Title
- Seawater adaptability and hormone levels in growth-enhanced transgenic coho salmon, Oncorhynchus kisutch
- Creators
- R.H Devlin - Fisheries and Oceans Canada, West Vancouver Laboratory, 4160 Marine Drive, West Vancouver, B.C., Canada V7V 1N6P Swanson - Northwest Fisheries Science Center, National Marine Fisheries Service, Seattle, WA 98112-2097, USAW.C Clarke - Fisheries and Oceans Canada, 3190 Hammond Bay Road, Nanaimo, B.C., Canada V9R 5K6E Plisetskaya - School of Fisheries, University of Washington, Seattle, WA 98195, USAW Dickhoff - School of Fisheries, University of Washington, Seattle, WA 98195, USAS Moriyama - School of Fisheries, University of Washington, Seattle, WA 98195, USAT.Y Yesaki - Fisheries and Oceans Canada, West Vancouver Laboratory, 4160 Marine Drive, West Vancouver, B.C., Canada V7V 1N6C.-L Hew - Department of Biochemistry and Clinical Biochemistry, University of Toronto, Toronto, Ontario, Canada M5G 1L5
- Publication Details
- Aquaculture, Vol.191(4), pp.367-385
- Academic Unit
- UNKNOWN
- Publisher
- Elsevier B.V
- Identifiers
- 99900548302101842
- Language
- English
- Resource Type
- Journal article