Journal article
Serious Mental Illness in Heavy Drinkers Is Associated with Poor Treatment Outcomes in Outpatients with Co-occurring Disorders
International journal of mental health and addiction, Vol.16(3), pp.672-679
06/2018
Handle:
https://hdl.handle.net/2376/111557
PMCID: PMC6027641
PMID: 29973859
Abstract
The objective of this study was to determine whether the interaction between type of serious mental illness (SMI) and pre-treatment drinking severity, assessed by ethyl glucuronide (EtG), predicts EtG-positive urine samples submitted during treatment in outpatients with co-occurring alcohol dependence and SMI. Seventy-nine participants were randomized to treatment-as-usual or treatment-as-usual and contingency management (CM) targeting alcohol abstinence. Generalized estimating equations were used to assess the interaction of pre-treatment drinking (heavy drinking or light drinking) and SMI diagnosis (major depression, bipolar, or schizophrenia-spectrum disorders) across a 12-week treatment period. In the overall sample, the interaction of drinking severity and SMI diagnosis (p = 0.006) was associated with alcohol abstinence. Exploratory analyses of the interaction term among participants randomized to CM (n = 40; p = 0.008) were associated with alcohol abstinence during CM. Type of SMI diagnosis was associated with treatment outcomes in individuals who engaged in heavy drinking, but not light drinking, prior to treatment.
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Details
- Title
- Serious Mental Illness in Heavy Drinkers Is Associated with Poor Treatment Outcomes in Outpatients with Co-occurring Disorders
- Creators
- Oladunni Oluwoye - 0000 0001 2157 6568 grid.30064.31 Program of Excellence in Addictions Research Washington State University Spokane WA USAEmily Leickly - 0000 0001 2157 6568 grid.30064.31 Program of Excellence in Addictions Research Washington State University Spokane WA USAJordan Skalisky - 0000 0001 2157 6568 grid.30064.31 Program of Excellence in Addictions Research Washington State University Spokane WA USASterling McPherson - Providence Medical Research Center Providence Health Care Spokane WA USAKatherine Hirchak - 0000 0001 2157 6568 grid.30064.31 Program of Excellence in Addictions Research Washington State University Spokane WA USADebra Srebnik - 0000000122986657 grid.34477.33 Department of Psychiatry and Behavioral Sciences University of Washington School of Medicine Seattle WA USAJohn Roll - 0000 0001 2157 6568 grid.30064.31 Elson S. Floyd College of Medicine Washington State University PO Box 1495 Spokane WA 99210-1495 USARichard Ries - 0000000122986657 grid.34477.33 Department of Psychiatry and Behavioral Sciences University of Washington School of Medicine Seattle WA USAMichael McDonell - 0000 0001 2157 6568 grid.30064.31 Elson S. Floyd College of Medicine Washington State University PO Box 1495 Spokane WA 99210-1495 USA
- Publication Details
- International journal of mental health and addiction, Vol.16(3), pp.672-679
- Academic Unit
- Elson S. Floyd College of Medicine; Medical Education and Clinical Science, Department of
- Publisher
- Springer US; New York
- Grant note
- R01 AA 02024801 / National Institute on Alcohol Abuse and Alcoholism (http://dx.doi.org/10.13039/100000027)
- Identifiers
- 99900547706001842
- Language
- English
- Resource Type
- Journal article