Significantly reduced cytochrome P450 3A4 expression and activity in liver from humans with diabetes mellitus

Journal article

Open access

Peer reviewed

Miroslav DOSTALEK, Michael H COURT, Bingfang YAN and Fatemeh AKHLAGHI

British journal of pharmacology, Vol.163(5), pp.937-947

2011

Handle:

https://hdl.handle.net/2376/115583

PMCID: PMC3130941

PMID: 21323901

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url

https://doi.org/10.1111/j.1476-5381.2011.01270.xView

Published (Version of record) Open

Diabetes. Impaired glucose tolerance

Pharmacology. Drug treatments

Biological and medical sciences

Endocrinopathies

Etiopathogenesis. Screening. Investigations. Target tissue resistance

Medical sciences

Endocrine pancreas. Apud cells (diseases)

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Title: Significantly reduced cytochrome P450 3A4 expression and activity in liver from humans with diabetes mellitus
Creators: Miroslav DOSTALEK - Department of Biomedical and Pharmaceutical Sciences, University of Rhode Island, Kingston, RI, United States
Michael H COURT - Molecular Pharmacogenetics Laboratory Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, Boston, MA, United States
Bingfang YAN - Department of Biomedical and Pharmaceutical Sciences, University of Rhode Island, Kingston, RI, United States
Fatemeh AKHLAGHI - Department of Biomedical and Pharmaceutical Sciences, University of Rhode Island, Kingston, RI, United States
Publication Details: British journal of pharmacology, Vol.163(5), pp.937-947
Academic Unit: Veterinary Clinical Sciences, Department of
Publisher: Nature Publishing Group; Basingstoke
Identifiers: 99900547859801842
Language: English
Resource Type: Journal article