Sociodemographic and clinical factors associated with depression in epilepsy

Alexander W Thompson; John W Miller; Wayne Katon; Naomi Chaytor; Paul Ciechanowski

doi:10.1016/j.yebeh.2009.02.014

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Sociodemographic and clinical factors associated with depression in epilepsy

Journal article

Open access

Peer reviewed

Sociodemographic and clinical factors associated with depression in epilepsy

Alexander W Thompson, John W Miller, Wayne Katon, Naomi Chaytor and Paul Ciechanowski

Epilepsy & behavior, Vol.14(4), pp.655-660

2009

DOI: https://doi.org/10.1016/j.yebeh.2009.02.014

Handle:

https://hdl.handle.net/2376/106493

PMCID: PMC2668729

PMID: 19233316

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https://doi.org/10.1016/j.yebeh.2009.02.014View

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Abstract

Depression

Case–control

Seizures

Epidemiology

Epilepsy

The impact of mood disorders on patients with epilepsy is an important and growing area of research. If clinicians are adept at recognizing which patients with epilepsy are at risk for mood disorders, treatment can be facilitated and morbidity avoided. We completed a case–control study (80 depressed subjects, 141 nondepressed subjects) to determine the sociodemographic and clinical factors associated with self-reported depression in people with epilepsy. The Patient Health Questionnaire-9 was used to determine clinically significant depression. In multivariate analyses, depressed subjects with epilepsy were significantly less likely than nondepressed subjects to be married or employed and more likely to report comorbid medical problems and active seizures in the past 6 months. Adjusted for all other variables, subjects with epilepsy reporting lamotrigine use were significantly less likely to be depressed (OR = 0.4, 95% CI: 0.2–0.8) compared with those not reporting lamotrigine use.

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Title: Sociodemographic and clinical factors associated with depression in epilepsy
Creators: Alexander W Thompson - Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA
John W Miller - University of Washington Regional Epilepsy Center, Harborview Medical Center, Seattle, WA, USA
Wayne Katon - Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA
Naomi Chaytor - University of Washington Regional Epilepsy Center, Harborview Medical Center, Seattle, WA, USA
Paul Ciechanowski - Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA
Publication Details: Epilepsy & behavior, Vol.14(4), pp.655-660
Academic Unit: Medical Education and Clinical Science, Department of
Publisher: Elsevier Inc
Identifiers: 99900546759901842
Language: English
Resource Type: Journal article