Journal article
Somatostatin-like immunoreactivity in the pituitary and brain of three teleost fish species: Somatostatin as a potential regulator of prolactin cell function
General and comparative endocrinology, Vol.59(3), pp.350-357
1985
Handle:
https://hdl.handle.net/2376/108812
PMID: 2864306
Abstract
Somatostatin-like immunofluorescence occurs in the hypothalamus and nurohypophysis of three euryhaline teleosts: tilapia, killifish, and mudsucker. This immunofluorescence was eliminated by incubating the primary antibody with excess somatostatin or somatostatin-28 but not with urotensin II, a partial analogue of somatostatin. In all fishes, the strongest reaction was seen in the proximal pars distalis and parts of the pars intermedia. Strongly fluorescing processes from cells of the preoptic nucleus extend toward the pituitary. Distinct fluorescence was also associated with the neurohypophysis penetrating into the rostral pars distalis in the tilapia but not in the killifish or mudsucker. In the tilapia, an extensive network of immunofluorescent fibers and small cells were present in the anterior dorsolateral telencephalon, in addition to a moderately fluorescing group of cells antero-lateral to the preoptic nucleus. A small area of diffuse fluorescence was also seen in the anterior dorsolateral midbrain tegmentum. Previous physiological studies have implicated somatostatin as a regulator or prolactin cell activit5y in tilapia. The present study demonstrates the route which somatostatin may be delivered to the rostral pars distalis to inhibit prolactin secretion.
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Details
- Title
- Somatostatin-like immunoreactivity in the pituitary and brain of three teleost fish species: Somatostatin as a potential regulator of prolactin cell function
- Creators
- E.Gordon Grau - Department of Zoology and Cancer Research Laboratory, University of California, Berkeley, California 94720, USARichard S Nishioka - Department of Zoology and Cancer Research Laboratory, University of California, Berkeley, California 94720, USAGraham Young - Department of Zoology and Cancer Research Laboratory, University of California, Berkeley, California 94720, USAHoward A Bern - Department of Zoology and Cancer Research Laboratory, University of California, Berkeley, California 94720, USA
- Publication Details
- General and comparative endocrinology, Vol.59(3), pp.350-357
- Academic Unit
- UNKNOWN
- Publisher
- Elsevier Inc
- Identifiers
- 99900547270701842
- Language
- English
- Resource Type
- Journal article