Journal article
Somnogenic activity of immune response modifiers
Trends in pharmacological sciences (Regular ed.), Vol.11(3), pp.122-126
1990
Handle:
https://hdl.handle.net/2376/113444
PMID: 2104463
Abstract
Sleepiness is a presenting symptom in nearly all infectious diseases. James Krueger
describes how microbial products, such as muramyl peptides, lipid A and double-stranded RNA, as well as endogenous products elicited by tnese substances, such as interleukin 1, modulate sleep. The altered sleep during infection seems to result from an exaggerated activation of physiological sleep mechanisms, since normal sleep is controlled by a wide range of substances including many of these immune response modifiers.
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Details
- Title
- Somnogenic activity of immune response modifiers
- Creators
- James M Krueger - J. M. Krueger is Professor at the Department of Physiology and Biophysics, College of Medicine, University of Tennessee Memphis, 894 Union Avenue, Memphis, TN 38163, USA
- Publication Details
- Trends in pharmacological sciences (Regular ed.), Vol.11(3), pp.122-126
- Academic Unit
- Integrative Physiology and Neuroscience, Department of
- Publisher
- Elsevier Ltd
- Identifiers
- 99900547684901842
- Language
- English
- Resource Type
- Journal article