Journal article
Stochastic Transmission of Multiple Genotypically Distinct Anaplasma marginale Strains in a Herd with High Prevalence of Anaplasma Infection
Journal of clinical microbiology, Vol.42(11), pp.5381-5384
11/2004
Handle:
https://hdl.handle.net/2376/114764
PMID: 15528749
Abstract
Multiple genotypically unique strains of the tick-borne pathogen
Anaplasma marginale
occur and are transmitted within regions where the organism is endemic. In this study, we tested the hypothesis that specific
A. marginale
strains are preferentially transmitted. The study herd of cattle (
n
= 261) had an infection prevalence of 29% as determined by competitive inhibition enzyme-linked immunosorbent assay and PCR, with complete concordance between results of the two assays. Genotyping revealed the presence of 11 unique strains within the herd. Although the majority of the individuals (70 of 75) were infected with only a single
A. marginale
strain, five animals each carried two strains with markedly distinct genotypes, indicating that superinfection does occur with distinct
A. marginale
strains, as has been reported with
A. marginale
and
A. marginale
subsp.
centrale
strains. Identification of strains in animals born into and infected within the herd during the period from 1998 to 2003 revealed no significant difference from the overall strain prevalence in the herd, results that do not support the occurrence of preferential strain transmission within a population of persistently infected animals and are most consistent with pathogen strain transmission being stochastic.
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Details
- Title
- Stochastic Transmission of Multiple Genotypically Distinct Anaplasma marginale Strains in a Herd with High Prevalence of Anaplasma Infection
- Creators
- Guy H Palmer - Program in Vector-borne Diseases, Washington State UniversityDonald P Knowles - Program in Vector-borne Diseases, Washington State UniversityJose-Luis Rodriguez - Program in Vector-borne Diseases, Washington State UniversityDavid P Gnad - Program in Vector-borne Diseases, Washington State UniversityLarry C Hollis - Program in Vector-borne Diseases, Washington State UniversityTwig Marston - Program in Vector-borne Diseases, Washington State UniversityKelly A Brayton - Program in Vector-borne Diseases, Washington State University
- Publication Details
- Journal of clinical microbiology, Vol.42(11), pp.5381-5384
- Academic Unit
- Veterinary Microbiology and Pathology, Department of; Paul G. Allen School for Global Animal Health
- Publisher
- American Society for Microbiology
- Identifiers
- 99900547897001842
- Language
- English
- Resource Type
- Journal article