Journal article
The CODATwins Project: The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits
Twin research and human genetics, Vol.18(4), pp.348-360
08/2015
Handle:
https://hdl.handle.net/2376/116083
PMCID: PMC4696543
PMID: 26014041
Abstract
For over 100 years, the genetics of human anthropometric traits has attracted scientific interest. In particular, height and body mass index (BMI, calculated as kg/m2) have been under intensive genetic research. However, it is still largely unknown whether and how heritability estimates vary between human populations. Opportunities to address this question have increased recently because of the establishment of many new twin cohorts and the increasing accumulation of data in established twin cohorts. We started a new research project to analyze systematically (1) the variation of heritability estimates of height, BMI and their trajectories over the life course between birth cohorts, ethnicities and countries, and (2) to study the effects of birth-related factors, education and smoking on these anthropometric traits and whether these effects vary between twin cohorts. We identified 67 twin projects, including both monozygotic (MZ) and dizygotic (DZ) twins, using various sources. We asked for individual level data on height and weight including repeated measurements, birth related traits, background variables, education and smoking. By the end of 2014, 48 projects participated. Together, we have 893,458 height and weight measures (52% females) from 434,723 twin individuals, including 201,192 complete twin pairs (40% monozygotic, 40% same-sex dizygotic and 20% opposite-sex dizygotic) representing 22 countries. This project demonstrates that large-scale international twin studies are feasible and can promote the use of existing data for novel research purposes.
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- Title
- The CODATwins Project: The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits
- Creators
- Karri Silventoinen - Department of Social Research, University of Helsinki, Helsinki, FinlandAline Jelenkovic - Department of Social Research, University of Helsinki, Helsinki, FinlandReijo Sund - Department of Social Research, University of Helsinki, Helsinki, FinlandChika Honda - Osaka University Graduate School of Medicine, Osaka University, Osaka, JapanSari Aaltonen - Department of Social Research, University of Helsinki, Helsinki, FinlandYoshie Yokoyama - Department of Public Health Nursing, Osaka City University, Osaka, JapanAdam D Tarnoki - Department of Radiology and Oncotherapy, Semmelweis University, Budapest, HungaryDavid L Tarnoki - Department of Radiology and Oncotherapy, Semmelweis University, Budapest, HungaryFeng Ning - Department of Noncommunicable Diseases Prevention, Qingdao Centers for Disease Control and Prevention, Qingdao, ChinaFuling Ji - Department of Noncommunicable Diseases Prevention, Qingdao Centers for Disease Control and Prevention, Qingdao, ChinaZengchang Pang - Department of Noncommunicable Diseases Prevention, Qingdao Centers for Disease Control and Prevention, Qingdao, ChinaJuan R Ordoñana - Department of Human Anatomy and Psychobiology, University of Murcia, Murcia, SpainJuan F Sánchez-Romera - IMIB-Arrixaca, Murcia, SpainLucia Colodro-Conde - Department of Human Anatomy and Psychobiology, University of Murcia, Murcia, SpainS. Alexandra Burt - 2 Michigan State University, East Lansing, MI, USAKelly L Klump - 2 Michigan State University, East Lansing, MI, USASarah E Medland - 1 QIMR Berghofer Medical Research Institute, Brisbane, Queensland, AustraliaGrant W Montgomery - 1 QIMR Berghofer Medical Research Institute, Brisbane, Queensland, AustraliaChristian Kandler - 3 Department of Psychology, Bielefeld University, Bielefeld, GermanyTom A McAdams - 4 MRC Social, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UKThalia C Eley - 4 MRC Social, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UKAlice M Gregory - 5 Department of Psychology, Goldsmiths, University of London, London, UKKimberly J Saudino - 6 Department of Psychological and Brain Sciences, Boston University, Boston, MA, USALise Dubois - 7 School of Epidemiology, Public Health and Preventive Medicine, University of Ottawa, Ottawa, Ontario, CanadaMichel Boivin - 8 École de psychologie, Université Laval, Québec, CanadaClaire M. A Haworth - 9 Department of Psychology, University of Warwick Coventry, Coventry, UKRobert Plomin - 4 MRC Social, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UKSevgi Y Öncel - 0 Department of Statistics, Faculty of Arts and Sciences, Kırıkkale University, Kırıkkale, TurkeyFazil Aliev - 1 Departments of Psychiatry, Psychology, and Human and Molecular Genetics, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USAMaria A Stazi - 3 Istituto Superiore di Sanità –– National Center for Epidemiology, Surveillance and Health Promotion, Rome, ItalyCorrado Fagnani - 3 Istituto Superiore di Sanità –– National Center for Epidemiology, Surveillance and Health Promotion, Rome, ItalyCristina D’Ippolito - 3 Istituto Superiore di Sanità –– National Center for Epidemiology, Surveillance and Health Promotion, Rome, ItalyJeffrey M Craig - 4 Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Victoria, AustraliaRichard Saffery - 4 Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Victoria, AustraliaSisira H Siribaddana - 6 Institute of Research & Development, Battaramulla, Sri LankaMatthew Hotopf - 8 NIHR Mental Health Biomedical Research Centre, South London and Maudsley NHS Foundation Trust and, Institute of Psychiatry Psychology and Neuroscience, King's College London, London, UKAthula Sumathipala - 6 Institute of Research & Development, Battaramulla, Sri LankaTimothy Spector - 0 Department of Twin Research and Genetic epidemiology, King's College, London, UKMassimo Mangino - 0 Department of Twin Research and Genetic epidemiology, King's College, London, UKGenevieve Lachance - 0 Department of Twin Research and Genetic epidemiology, King's College, London, UKMargaret Gatz - 1 Department of Psychology, University of Southern California, Los Angeles, CA, USADavid A Butler - 2 Institute of Medicine, National Academy of Sciences, Washington, DC, USAGombojav Bayasgalan - 3 Healthy Twin Association of Mongolia, Ulaanbaatar, MongoliaDanshiitsoodol Narandalai - 3 Healthy Twin Association of Mongolia, Ulaanbaatar, MongoliaDuarte L Freitas - 5 Department of Physical Education and Sport, University of Madeira, Funchal, PortugalJosé Antonio Maia - 6 CIFI2D, Faculty of Sport, University of Porto, Porto, PortugalK. Paige Harden - 7 Department of Psychology, University of Texas at Austin, Austin, TX, USAElliot M Tucker-Drob - 7 Department of Psychology, University of Texas at Austin, Austin, TX, USAKaare Christensen - 8 The Danish Twin Registry, Institute of Public Health, Epidemiology, Biostatistics & Biodemography, University of Southern Denmark, Odense, DenmarkAxel Skytthe - 8 The Danish Twin Registry, Institute of Public Health, Epidemiology, Biostatistics & Biodemography, University of Southern Denmark, Odense, DenmarkKirsten O Kyvik - 0 Department of Clinical Research, University of Southern Denmark, Odense, DenmarkChanghee Hong - 2 Department of Psychology, Pusan National University, Busan, South KoreaYoungsook Chong - 2 Department of Psychology, Pusan National University, Busan, South KoreaCatherine A Derom - 3 Centre of Human Genetics, University Hospitals Leuven, Leuven, BelgiumRobert F Vlietinck - 3 Centre of Human Genetics, University Hospitals Leuven, Leuven, BelgiumRuth J. F Loos - 4 The Charles Bronfman Institute for Personalized Medicine, The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USAWendy Cozen - 5 Department of Preventive Medicine, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USAAmie E Hwang - 5 Department of Preventive Medicine, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USAThomas M Mack - 5 Department of Preventive Medicine, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USAMingguang He - 7 State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, ChinaXiaohu Ding - 7 State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, ChinaBilly Chang - 7 State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, ChinaJudy L Silberg - 9 Department of Human and Molecular Genetics, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USALindon J Eaves - 9 Department of Human and Molecular Genetics, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USAHermine H Maes - 0 Department of Human and Molecular Genetics, Psychiatry & Massey Cancer Center, Virginia Commonwealth University, Richmond, VA, USATessa L Cutler - 1 The Australian Twin Registry, Centre for Epidemiology and Biostatistics, The University of Melbourne, Melbourne, Victoria, AustraliaJohn L Hopper - 1 The Australian Twin Registry, Centre for Epidemiology and Biostatistics, The University of Melbourne, Melbourne, Victoria, AustraliaKelly Aujard - 3 Centre for Epidemiology and Biostatistics, The University of Melbourne, Melbourne, Victoria, AustraliaPatrik K. E Magnusson - 4 Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SwedenNancy L Pedersen - 4 Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SwedenAnna K. Dahl Aslan - 4 Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SwedenYun-Mi Song - 6 Department of Family Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South KoreaSarah Yang - 2 Department of Epidemiology, School of Public Health, Seoul National University, Seoul, South KoreaKayoung Lee - 8 Department of Family Medicine, Busan Paik Hospital, Inje University College of Medicine, Busan, South KoreaLaura A Baker - 1 Department of Psychology, University of Southern California, Los Angeles, CA, USACatherine Tuvblad - 1 Department of Psychology, University of Southern California, Los Angeles, CA, USAMorten Bjerregaard-Andersen - 0 Bandim Health Project, INDEPTH Network, Apartado, Bissau Codex, Guinea-BissauHenning Beck-Nielsen - 2 Department of Endocrinology, Odense University Hospital, Odense, DenmarkMorten Sodemann - 3 Department of Infectious Diseases, Odense University Hospital, Odense, DenmarkKauko Heikkilä - Department of Public Health, University of Helsinki, Helsinki, FinlandQihua Tan - 4 Epidemiology, Biostatistics and Biodemography, Institute of Public Health, University of Southern Denmark, Odense, DenmarkDongfeng Zhang - 5 Department of Public Health, Qingdao University Medical College, Qingdao, ChinaGary E Swan - 6 Stanford Prevention Research Center, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USARuth Krasnow - 7 Center for Health Sciences, SRI International, Menlo Park, CA, USAKerry L Jang - 8 Department of Psychiatry, University of British Columbia, Vancouver, British Columbia, CanadaAriel Knafo-Noam - 9 The Hebrew University of Jerusalem, Jerusalem, IsraelDavid Mankuta - 0 Hadassah Hospital Obstetrics and Gynecology Department, Hebrew University Medical School, Jerusalem, IsraelLior Abramson - 9 The Hebrew University of Jerusalem, Jerusalem, IsraelPaul Lichtenstein - 4 Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SwedenRobert F Krueger - 1 Department of Psychology, University of Minnesota, Minneapolis, MN, USAMatt McGue - 1 Department of Psychology, University of Minnesota, Minneapolis, MN, USAShandell Pahlen - 1 Department of Psychology, University of Minnesota, Minneapolis, MN, USAPer Tynelius - 2 Department of Public Health Sciences, Karolinska Institutet, Stockholm, SwedenGlen E Duncan - 3 Center for Clinical and Epidemiological Research, University of Washington, Seattle, WA, USADedra Buchwald - 3 Center for Clinical and Epidemiological Research, University of Washington, Seattle, WA, USARobin P Corley - 4 Institute for Behavioral Genetics, Boulder, CO, USABrooke M Huibregtse - 4 Institute for Behavioral Genetics, Boulder, CO, USATracy L Nelson - 5 Department of Health and Exercise Sciences and Colorado School of Public Health, Colorado State University, Fort Collins, CO, USAKeith E Whitfield - 6 Psychology and Neuroscience, Duke University, Durham, NC, USACarol E Franz - 7 Department of Psychiatry, University of California, San Diego, CA, USAWilliam S Kremen - 7 Department of Psychiatry, University of California, San Diego, CA, USAMichael J Lyons - 9 Boston University, Department of Psychology, Boston, MA, USASyuichi Ooki - 0 Department of Health Science, Ishikawa Prefectural Nursing University, Kahoku, Ishikawa, JapanIngunn Brandt - 1 Norwegian Institute of Public Health, Division of Epidemiology, Department of Genes and Environment, Oslo, NorwayThomas Sevenius Nilsen - 1 Norwegian Institute of Public Health, Division of Epidemiology, Department of Genes and Environment, Oslo, NorwayFujio Inui - Osaka University Graduate School of Medicine, Osaka University, Osaka, JapanMikio Watanabe - Osaka University Graduate School of Medicine, Osaka University, Osaka, JapanMeike Bartels - 3 Department of Biological Psychology, VU University Amsterdam, Amsterdam, NetherlandsToos C. E. M van Beijsterveldt - 3 Department of Biological Psychology, VU University Amsterdam, Amsterdam, NetherlandsJane Wardle - 4 Health Behaviour Research Centre, Department of Epidemiology and Public Health, Institute of Epidemiology and Health Care, University College London, London, UKClare H Llewellyn - 4 Health Behaviour Research Centre, Department of Epidemiology and Public Health, Institute of Epidemiology and Health Care, University College London, London, UKAbigail Fisher - 4 Health Behaviour Research Centre, Department of Epidemiology and Public Health, Institute of Epidemiology and Health Care, University College London, London, UKEsther Rebato - Department of Genetics, Physical Anthropology and Animal Physiology, University of the Basque Country UPV/EHU, Leioa, SpainNicholas G Martin - 1 QIMR Berghofer Medical Research Institute, Brisbane, Queensland, AustraliaYoshinori Iwatani - Osaka University Graduate School of Medicine, Osaka University, Osaka, JapanKazuo Hayakawa - Osaka University Graduate School of Medicine, Osaka University, Osaka, JapanFinn Rasmussen - 2 Department of Public Health Sciences, Karolinska Institutet, Stockholm, SwedenJoohon Sung - 2 Department of Epidemiology, School of Public Health, Seoul National University, Seoul, South KoreaJennifer R Harris - 1 Norwegian Institute of Public Health, Division of Epidemiology, Department of Genes and Environment, Oslo, NorwayGonneke Willemsen - 3 Department of Biological Psychology, VU University Amsterdam, Amsterdam, NetherlandsAndreas Busjahn - 5 HealthTwiSt GmbH, Berlin, GermanyJack H Goldberg - 6 Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USADorret I Boomsma - 3 Department of Biological Psychology, VU University Amsterdam, Amsterdam, NetherlandsYoon-Mi Hur - 7 Department of Education, Mokpo National University, Jeonnam, South KoreaThorkild I. A Sørensen - 8 Novo Nordisk Foundation Centre for Basic Metabolic Research, Section on Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, DenmarkJaakko Kaprio - Department of Public Health, University of Helsinki, Helsinki, Finland
- Publication Details
- Twin research and human genetics, Vol.18(4), pp.348-360
- Academic Unit
- Community Health; Nutrition and Exercise Physiology, Department of
- Publisher
- Cambridge University Press; Cambridge, UK
- Number of pages
- 13
- Identifiers
- 99900547676301842
- Language
- English
- Resource Type
- Journal article