Journal article
The central role of Sertoli cells in spermatogenesis
Seminars in cell & developmental biology, Vol.9(4), pp.411-416
08/1998
Handle:
https://hdl.handle.net/2376/118098
PMID: 9813187
Abstract
Sertoli cells are the somatic cells of the testis that are essential for testis formation and spermatogenesis. Sertoli cells facilitate the progression of germ cells to spermatozoa via direct contact and by controlling the environment milieu within the seminiferous tubules. The regulation of spermatogenesis by FSH and testosterone occurs by the action of these hormones on the Sertoli cells. While the action of testosterone is necessary for spermatogenesis, the action of FSH minimally serves to promote spermatogenic output by increasing the number of Sertoli cells.
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Details
- Title
- The central role of Sertoli cells in spermatogenesis
- Creators
- Michael D Griswold - Department of Biochemistry and Biophysics, Washington State University, Pullman, WA, 99164-4660, USA
- Publication Details
- Seminars in cell & developmental biology, Vol.9(4), pp.411-416
- Academic Unit
- Molecular Biosciences, School of
- Publisher
- Elsevier Ltd
- Identifiers
- 99900547818001842
- Language
- English
- Resource Type
- Journal article