Journal article
The complexity of simplicity: Role of sex, development, and environment in modulation of the stress response
Journal of neuroendocrinology, Vol.28(8), pp.np-n/a
08/2016
Handle:
https://hdl.handle.net/2376/106417
PMCID: PMC5007192
PMID: 27005563
Abstract
Anecdotally, we all know stress is “complicated”, but most stress research is undertaken using incredibly simplified models that may not allow us to fully understand underlying interactive mechanisms that are present in the “real world”. This attempt at simplification, while sometimes necessary, may explain some of the difficulties in translating basic science findings to the clinical and epidemiological data on stress and stress-related disorders. In a symposium at the 2015 International Society for Psychoneuroendocrinology meeting in Edinburgh, UK, a series of speakers explored “
The many pathways to plasticity in the stress system”
, specifically focusing on variables that are in many cases eliminated from studies of stress in order to provide increased experimental control. Specifically, four speakers tackled the complex contributions of
Sex, Development
, and
Environment
in stress research, providing evidence from published and unpublished work from their own laboratories demonstrating that in our race for simplicity in experimentation, the stories we tell become all the more complex.
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Details
- Title
- The complexity of simplicity: Role of sex, development, and environment in modulation of the stress response
- Creators
- Ilia N Karatsoreos - Department of Integrative Physiology and Neuroscience, Washington State University
- Publication Details
- Journal of neuroendocrinology, Vol.28(8), pp.np-n/a
- Academic Unit
- Integrative Physiology and Neuroscience, Department of
- Identifiers
- 99900546839701842
- Language
- English
- Resource Type
- Journal article