The function of calreticulin in plant immunity: new discoveries for an old protein

Yongjian Qiu; Jing Xi; Liqun Du; B W Poovaiah

doi:10.4161/psb.20721

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The function of calreticulin in plant immunity: new discoveries for an old protein

Journal article

Open access

Peer reviewed

The function of calreticulin in plant immunity: new discoveries for an old protein

Yongjian Qiu, Jing Xi, Liqun Du and B W Poovaiah

Plant signaling & behavior, Vol.7(8), pp.907-910

08/2012

DOI: https://doi.org/10.4161/psb.20721

Handle:

https://hdl.handle.net/2376/116294

PMCID: PMC3474682

PMID: 22827946

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Abstract

Amino Acid Sequence

Plant Immunity

Humans

Arabidopsis - immunology

Molecular Sequence Data

Mutation - genetics

Subcellular Fractions - metabolism

Arabidopsis - metabolism

Protein Transport

Arabidopsis - genetics

Arabidopsis Proteins - metabolism

Calreticulin - chemistry

Phenotype

Animals

Arabidopsis Proteins - chemistry

Plants, Genetically Modified

Calreticulin - metabolism

Since its initial discovery as a high affinity Ca ( 2+) -binding protein in the sarcoplasmic reticulum and endoplasmic reticulum (ER), calreticulin (CRT) has been documented to be a multifunctional protein in both animal and plant cells. This protein is well recognized as a Ca ( 2+) -binding molecular chaperone that facilitates the folding of newly synthesized glycoproteins and regulates the Ca ( 2+) homeostasis in the ER lumen. However, functional relevance associated with its localization in other cellular compartments has also been reported. Recent studies suggest that both isoforms of plant CRTs (AtCRT1/2 and AtCRT3) are involved in regulating plant defense against biotrophic pathogens. Here we discuss the cellular functions of CRT and its connection to the emerging functions of AtCRTs in plant immunity.

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Title: The function of calreticulin in plant immunity: new discoveries for an old protein
Creators: Yongjian Qiu - Department of Horticulture, Washington State University, Pullman, Washington, USA
Jing Xi
Liqun Du
B W Poovaiah
Publication Details: Plant signaling & behavior, Vol.7(8), pp.907-910
Academic Unit: Horticulture, Department of
Publisher: United States
Identifiers: 99900547857401842
Language: English
Resource Type: Journal article