Journal article
The key role of vitamin A in spermatogenesis
The Journal of clinical investigation, Vol.120(4), pp.956-962
04/2010
Handle:
https://hdl.handle.net/2376/110756
PMCID: PMC2846058
PMID: 20364093
Abstract
Spermatogenesis in adult mammals is highly organized, with the goal being continual sperm production. Vertebrate testes are arranged into recurring cellular associations that vary with time and distance along the tubule. These changes over time and distance are designated the cycle of the seminiferous epithelium and the spermatogenic wave, respectively. In this Review, we briefly outline the roles that follicle-stimulating hormone (FSH) and testosterone play in regulating spermatogenesis and describe our current understanding of how vitamin A regulates germ cell differentiation and how it may lead to the generation of both the cycle of the seminiferous epithelium and the spermatogenic wave.
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Details
- Title
- The key role of vitamin A in spermatogenesis
- Creators
- Cathryn A Hogarth - School of Molecular Biosciences, Washington State University, Pullman, WA 99164-7520, USAMichael D Griswold
- Publication Details
- The Journal of clinical investigation, Vol.120(4), pp.956-962
- Academic Unit
- Molecular Biosciences, School of
- Publisher
- United States
- Grant note
- R37 HD010808 / NICHD NIH HHS R01 HD010808 / NICHD NIH HHS U54 42454 / PHS HHS HD 10808-33 / NICHD NIH HHS
- Identifiers
- 99900547109101842
- Language
- English
- Resource Type
- Journal article