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The min K channel underlies the cardiac potassium current I(Ks) and mediates species-specific responses to protein kinase C
Journal article   Open access

The min K channel underlies the cardiac potassium current I(Ks) and mediates species-specific responses to protein kinase C

Michael D Varnum, Andreas E Busch, Chris T Bond, James Maylie and John P Adelman
Proceedings of the National Academy of Sciences - PNAS, Vol.90(24), pp.11528-11532
12/15/1993
DOI: https://doi.org/10.1073/pnas.90.24.11528
Handle:
https://hdl.handle.net/2376/117231
PMID: 8265583
url
https://doi.org/10.1073/pnas.90.24.11528View
Published (Version of record) Open

Abstract

Proteins Heart Research Anatomy & physiology Rodents
  Research supports the hypothesis that the min K protein underlies the slow component of the delayed rectifier potassium current in ventricular myocytes and account for the species-specific responses to stimulation of protein kinase C. The cloning and expression in Xenopus oocytes of the guinea pig min K protein are described.

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