Journal article
The white-rot fungus Phanerochaete chrysosporium: conditions for the production of lignin-degrading enzymes
Applied microbiology and biotechnology, Vol.81(3), pp.399-417
12/2008
Handle:
https://hdl.handle.net/2376/113279
PMID: 18810426
Abstract
Investigating optimal conditions for lignin-degrading peroxidases production by Phanerochaete chrysosporium (P. chrysosporium) has been a topic for numerous researches. The capability of P. chrysosporium for producing lignin peroxidases (LiPs) and manganese peroxidases (MnPs) makes it a model organism of lignin-degrading enzymes production. Focusing on compiling and identifying the factors that affect LiP and MnP production by P. chrysosporium, this critical review summarized the main findings of about 200 related research articles. The major difficulty in using this organism for enzyme production is the instability of its productivity. This is largely due to the poor understanding of the regulatory mechanisms of P. chrysosporium responding to different nutrient sources in the culture medium, such as metal elements, detergents, lignin materials, etc. In addition to presenting the major conclusions and gaps of the current knowledge on lignin-degrading peroxidases production by P. chrysosporium, this review has also suggested further work, such as correlating the overexpression of the intra and extracellular proteins to the nutrients and other culture conditions to discover the regulatory cascade in the lignin-degrading peroxidases production process, which may contribute to the creation of improved P. chrysosporium strains leading to stable enzyme production.
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Details
- Title
- The white-rot fungus Phanerochaete chrysosporium: conditions for the production of lignin-degrading enzymes
- Creators
- Deepak Singh - Department of Biological Systems Engineering and Center for Bioproducts and Bioenergy, Washington State University, L.J. Smith 213, Pullman, WA 99163, USAShulin Chen
- Publication Details
- Applied microbiology and biotechnology, Vol.81(3), pp.399-417
- Academic Unit
- Biological Systems Engineering, Department of
- Publisher
- Germany
- Identifiers
- 99900547331201842
- Language
- English
- Resource Type
- Journal article