Journal article
Thiamylal‐Sparing Effect of Midazolam for Canine Endotracheal Intubation A Clinical Study of 118 Dogs
Veterinary surgery, Vol.22(1), pp.69-72
01/1993
Handle:
https://hdl.handle.net/2376/107122
PMID: 8488679
Abstract
One hundred eighteen dogs were studied at three veterinary teaching hospitals after the administration of midazolam (0.1 mg/kg, intravenously [IV]) or a placebo. Midazolam and placebo treatments were randomized and blinded to the investigators. The dose of thiamylal required for tracheal intubation 3 to 5 minutes after midazolam or placebo was calculated. The dose of thiamylal at the three hospitals was 10.6,9.8, and 10.1 mg/kg IV after midazolam, and 12.1,11.2, and 11.6 mg/kg IV after placebo. Pooled data from the three hospitals yielded a significant (p < .001) decrease in mean IV thiamylal dose after midazolam (10.2 mg/kg) compared with placebo (11.6 mg/kg). Overall, there was a 12% decrease in the dose of thiamylal required for tracheal intubation after midazolam compared to that after the placebo. The thiamylal dose was significantly (p < .001) decreased after midazolam compared with placebo for dogs weighing more than 15 kg but not for dogs weighing less than 15 kg.
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Details
- Title
- Thiamylal‐Sparing Effect of Midazolam for Canine Endotracheal Intubation A Clinical Study of 118 Dogs
- Creators
- STEPHEN A GREENEG. JOHN BENSONSANDEE M HARTSFIELD
- Publication Details
- Veterinary surgery, Vol.22(1), pp.69-72
- Academic Unit
- Veterinary Clinical Sciences, Department of
- Publisher
- Blackwell Publishing Ltd; Oxford, UK
- Number of pages
- 4
- Identifiers
- 99900546768301842
- Language
- English
- Resource Type
- Journal article