Toward understanding how the lactone moiety of discodermolide affects activity

Journal article

Simon J SHAW, Kurt F SUNDERMANN, Mark A BURLINGAME, David C MYLES, B. Scott FREEZE, Ming Xian, Ignacio BROUARD and Amos B SMITH

Journal of the American Chemical Society, Vol.127(18), pp.6532-6533

2005

Handle:

https://hdl.handle.net/2376/107986

PMID: 15869264

Abstract

Biological and medical sciences

Physicochemical properties. Structure-activity relationships

Medical sciences

General pharmacology

Pharmacology. Drug treatments

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Title: Toward understanding how the lactone moiety of discodermolide affects activity
Creators: Simon J SHAW - Kosan Biosciences, Inc., 3832 Bay Center Place, Hayward, California 94545, United States
Kurt F SUNDERMANN - Kosan Biosciences, Inc., 3832 Bay Center Place, Hayward, California 94545, United States
Mark A BURLINGAME - Kosan Biosciences, Inc., 3832 Bay Center Place, Hayward, California 94545, United States
David C MYLES - Kosan Biosciences, Inc., 3832 Bay Center Place, Hayward, California 94545, United States
B. Scott FREEZE - University of Pennsylvania, Department of Chemistry, Philadelphia, Pennsylvania 19104, United States
Ming Xian - University of Pennsylvania, Department of Chemistry, Philadelphia, Pennsylvania 19104, United States
Ignacio BROUARD - University of Pennsylvania, Department of Chemistry, Philadelphia, Pennsylvania 19104, United States
Amos B SMITH - University of Pennsylvania, Department of Chemistry, Philadelphia, Pennsylvania 19104, United States
Publication Details: Journal of the American Chemical Society, Vol.127(18), pp.6532-6533
Academic Unit: Department of Chemistry
Publisher: American Chemical Society; Washington, DC
Identifiers: 99900547753701842
Language: English
Resource Type: Journal article