Journal article
Transmission of Anaplasma marginale by Boophilus microplus: Retention of Vector Competence in the Absence of Vector-Pathogen Interaction
Journal of clinical microbiology, Vol.41(8), pp.3829-3834
08/2003
Handle:
https://hdl.handle.net/2376/114727
PMCID: PMC179812
PMID: 12904396
Abstract
Whether arthropod vectors retain competence for transmission of infectious agents in the long-term absence of vector-pathogen interaction is unknown. We addressed this question by quantifying the vector competence of two tick vectors, with mutually exclusive tropical- versus temperate-region distributions, for genetically distinct tropical- and temperate-region strains of the cattle pathogen
Anaplasma marginale
. The tropical cattle tick
Boophilus microplus
, which has been eradicated from the continental United States for over 60 years, was able to acquire and transmit the temperate St. Maries (Idaho) strain of
A. marginale
. Similarly, the temperate-region tick
Dermacentor andersoni
efficiently acquired and transmitted the Puerto Rico strain of
A. marginale
. There were no significant quantitative differences in infection rate or number of organisms per tick following feeding on cattle with persistent infections of either
A. marginale
strain. In contrast, the significantly enhanced replication of the Puerto Rico strain in the salivary gland of
B. microplus
at the time of transmission feeding is consistent with adaptation of a pathogen strain to its available vector. However, the transmission of both strains by
B. microplus
demonstrates that adaptation or continual interaction between the pathogen and vector is not required for retention of vector competence. Importantly, the results clearly show that reestablishment of acaricide-resistant
B. microplus
in the United States would be associated with
A. marginale
transmission.
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Details
- Title
- Transmission of Anaplasma marginale by Boophilus microplus: Retention of Vector Competence in the Absence of Vector-Pathogen Interaction
- Creators
- James E Futse - Program in Vector-Borne Diseases, Department of Veterinary Microbiology and Pathology, Washington State UniversityMassaro W Ueti - Program in Vector-Borne Diseases, Department of Veterinary Microbiology and Pathology, Washington State UniversityDonald P Knowles - Program in Vector-Borne Diseases, Department of Veterinary Microbiology and Pathology, Washington State UniversityGuy H Palmer - Program in Vector-Borne Diseases, Department of Veterinary Microbiology and Pathology, Washington State University
- Publication Details
- Journal of clinical microbiology, Vol.41(8), pp.3829-3834
- Academic Unit
- Veterinary Microbiology and Pathology, Department of; Paul G. Allen School for Global Animal Health
- Publisher
- American Society for Microbiology
- Identifiers
- 99900547965601842
- Language
- English
- Resource Type
- Journal article