Journal article
Treatment of chorea associated with Huntington's disease: focus on tetrabenazine
The Consultant pharmacist, Vol.24(7), pp.524-537
07/2009
Handle:
https://hdl.handle.net/2376/118212
PMID: 19689181
Abstract
Review Huntington's disease (HD) and the role of tetrabenazine (TBZ) in treating chorea associated with this disease. Discuss the pharmacology, side-effect profile, drug interactions, precautions, and contraindications of TBZ.
Literature identified within MEDLINE and PubMED.
Two manuscripts specifically regarding the management of chorea in patients with HD were identified. Additionally, studies involving the clinical use of TBZ were reviewed.
The literature identified provided information regarding the efficacy, safety, and pharmacological actions of TBZ.
HD is often accompanied by chorea, and the treatment with TBZ in this patient population often results in decreased chorea. Pharmacists managing patients on TBZ need to be well versed in TBZ's potential side effects, drug interactions, and unique dosing considerations.
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Details
- Title
- Treatment of chorea associated with Huntington's disease: focus on tetrabenazine
- Creators
- Stephen M Setter - Washington State University/Elder Sevices, Spokane, Washington 99217, USA. ssetter@smhca.orgJoshua J NeumillerErin K DobbinsLindy WoodJeffrey ClarkCristina A K DuVallAnthony Santiago
- Publication Details
- The Consultant pharmacist, Vol.24(7), pp.524-537
- Academic Unit
- Pharmacotherapy, Department of
- Publisher
- United States
- Identifiers
- 99900548276401842
- Language
- English
- Resource Type
- Journal article