Journal article
Trends in cell-based electrochemical biosensors
Current medicinal chemistry, Vol.15(30), pp.3160-3170
2008
Handle:
https://hdl.handle.net/2376/112329
PMID: 19075660
Abstract
Cell-based electrochemical biosensors have contributed tremendously to the fields of biology, medicine, chemistry, pharmacology, and environmental science. With electrochemical transducers and whole cells as the recognition elements, these biosensors provide new horizons for biosensing and life science research. This review focuses on the research accomplishments on this topic over the last three years, and is divided into three sections according to the types of cellular responses. Our aim is to highlight how simple and sensitive electrochemical methods can be coupled with cells by virtue of the integration of interface control, nanotechnology and genetic engineering to generate new enabling technologies. Some specific examples to demonstrate how these sensors are useful in medicinal chemistry and drug design have also been discussed. It is hoped that this review can provide inspiration for the development of fast, selective, sensitive, and convenient detection and diagnosis platforms.
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Details
- Title
- Trends in cell-based electrochemical biosensors
- Creators
- Lin Ding - Key Laboratory of Analytical Chemistry for Life Sciences (Ministry of Education of China), Department of Chemistry, Nanjing University, Nanjing 210093, P. R. ChinaDan DuXueji ZhangHuangxian Ju
- Publication Details
- Current medicinal chemistry, Vol.15(30), pp.3160-3170
- Academic Unit
- School of Mechanical and Materials Engineering
- Publisher
- United Arab Emirates
- Identifiers
- 99900547600301842
- Language
- English
- Resource Type
- Journal article