Journal article
Trisomy in humans: incidence, origin and etiology
Current opinion in genetics & development, Vol.3(3), pp.398-403
1993
Handle:
https://hdl.handle.net/2376/108425
PMID: 8353412
Abstract
Molecular studies conducted over the past year have demonstrated the importance of aberrant genetic recombination in the etiology of several human trisomies, and have begun to shed light on the basis of the association between advancing maternal age and trisomy. Preliminary studies of gametes using fluorescence in situ hybridization indicate that this will be a useful approach in the analysis of human non-disjunction.
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Details
- Title
- Trisomy in humans: incidence, origin and etiology
- Creators
- Terry Hassold - Department of Genetics, Case Western Reserve University, Cleveland, Ohio 44106, USAPatricia A Hunt - Department of Genetics, Case Western Reserve University, Cleveland, Ohio 44106, USAStephanie Sherman - Department of Genetics, Emory University, Atlanta, Georgia 30322, USA
- Publication Details
- Current opinion in genetics & development, Vol.3(3), pp.398-403
- Academic Unit
- Molecular Biosciences, School of
- Publisher
- Elsevier Ltd
- Identifiers
- 99900547192501842
- Language
- English
- Resource Type
- Journal article