Journal article
Type of alcoholic beverage and risk of head and neck cancer--a pooled analysis within the INHANCE Consortium
American journal of epidemiology, Vol.169(2), pp.132-142
01/15/2009
Handle:
https://hdl.handle.net/2376/112248
PMCID: PMC2727255
PMID: 19064644
Abstract
The authors pooled data from 15 case-control studies of head and neck cancer (9,107 cases, 14,219 controls) to investigate the independent associations with consumption of beer, wine, and liquor. In particular, they calculated associations with different measures of beverage consumption separately for subjects who drank beer only (858 cases, 986 controls), for liquor-only drinkers (499 cases, 527 controls), and for wine-only drinkers (1,021 cases, 2,460 controls), with alcohol never drinkers (1,124 cases, 3,487 controls) used as a common reference group. The authors observed similar associations with ethanol-standardized consumption frequency for beer-only drinkers (odds ratios (ORs) = 1.6, 1.9, 2.2, and 5.4 for < or =5, 6-15, 16-30, and >30 drinks per week, respectively; P(trend) < 0.0001) and liquor-only drinkers (ORs = 1.6, 1.5, 2.3, and 3.6; P < 0.0001). Among wine-only drinkers, the odds ratios for moderate levels of consumption frequency approached the null, whereas those for higher consumption levels were comparable to those of drinkers of other beverage types (ORs = 1.1, 1.2, 1.9, and 6.3; P < 0.0001). Study findings suggest that the relative risks of head and neck cancer for beer and liquor are comparable. The authors observed weaker associations with moderate wine consumption, although they cannot rule out confounding from diet and other lifestyle factors as an explanation for this finding. Given the presence of heterogeneity in study-specific results, their findings should be interpreted with caution.
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Details
- Title
- Type of alcoholic beverage and risk of head and neck cancer--a pooled analysis within the INHANCE Consortium
- Creators
- Mark P Purdue - National Cancer Institute, Bethesda, Maryland, USA. purduem@mail.nih.govPhilip LazarusMia HashibeJulien BerthillerCarlo La VecchiaLuigino Dal MasoRolando HerreroSilvia FranceschiXavier CastellsagueQingyi WeiErich M SturgisHal MorgensternZuo-Feng ZhangFabio LeviRenato TalaminiElaine SmithJoshua MuscatStephen M SchwartzChu ChenJose Eluf NetoVictor Wünsch-FilhoDavid ZaridzeSergio KoifmanMaria Paula CuradoSimone BenhamouElena MatosNeonilia Szeszenia-DabrowskaAndrew F OlshanJuan LenceAna MenezesAlexander W DaudtIoan Nicolae MatesAgnieszka PilarskaEleonora FabianovaPeter RudnaiDebbie WinnGilles FerroPaul BrennanPaolo BoffettaRichard B Hayes
- Publication Details
- American journal of epidemiology, Vol.169(2), pp.132-142
- Academic Unit
- Department of Pharmaceutical Sciences
- Publisher
- Oxford Univ Press; United States
- Number of pages
- 11
- Grant note
- R03CA77954 / NCI NIH HHS T32 CA009142 / NCI NIH HHS TW01500 / FIC NIH HHS R01DE11979 / NIDCR NIH HHS R01DE13110 / NIDCR NIH HHS R21ES011667 / NIEHS NIH HHS R01 DE013110 / NIDCR NIH HHS Intramural NIH HHS R01CA048896 / NCI NIH HHS R03 TW001500 / FIC NIH HHS P30 ES010126 / NIEHS NIH HHS R01ES11740 / NIEHS NIH HHS R01DA11386 / NIDA NIH HHS P50CA90388 / NCI NIH HHS R24 HD050924 / NICHD NIH HHS R01DE012609 / NIDCR NIH HHS K07 CA104231 / NCI NIH HHS U01 CA096134 / NCI NIH HHS R01 DA011386 / NIDA NIH HHS P30ES010126 / NIEHS NIH HHS P01 CA068384 / NCI NIH HHS U01CA96134 / NCI NIH HHS R03 CA077954 / NCI NIH HHS R21 ES011667 / NIEHS NIH HHS T32CA09142 / NCI NIH HHS P50 CA090388 / NCI NIH HHS P01CA068384 / NCI NIH HHS K07CA104231 / NCI NIH HHS R01 ES011740 / NIEHS NIH HHS R01CA61188 / NCI NIH HHS R01CA100264 / NCI NIH HHS R01 CA100264 / NCI NIH HHS
- Identifiers
- 99900547304601842
- Language
- English
- Resource Type
- Journal article