Validation of serotonin (5-hydroxtryptamine) as an in vitro substrate probe for human UDP-glucuronosyltransferase (UGT) 1A6

Journal article

Peer reviewed

Soundararajan KRISHNASWAMY, Su X DUAN, Lisa L VON MOLTKE, David J GREENBLATT and Michael H COURT

Drug metabolism and disposition, Vol.31(1), pp.133-139

2003

Handle:

https://hdl.handle.net/2376/112737

PMID: 12485962

Abstract

Fundamental and applied biological sciences. Psychology

Biological and medical sciences

Analytical, structural and metabolic biochemistry

Enzymes and enzyme inhibitors

Transferases

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Title: Validation of serotonin (5-hydroxtryptamine) as an in vitro substrate probe for human UDP-glucuronosyltransferase (UGT) 1A6
Creators: Soundararajan KRISHNASWAMY - Comparative and Molecular Pharmacogenetics Laboratory, Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, Boston, Massachusetts, United States
Su X DUAN - Comparative and Molecular Pharmacogenetics Laboratory, Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, Boston, Massachusetts, United States
Lisa L VON MOLTKE - Clinical Pharmacology Laboratory, Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, Boston, Massachusetts, United States
David J GREENBLATT - Clinical Pharmacology Laboratory, Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, Boston, Massachusetts, United States
Michael H COURT - Comparative and Molecular Pharmacogenetics Laboratory, Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, Boston, Massachusetts, United States
Publication Details: Drug metabolism and disposition, Vol.31(1), pp.133-139
Academic Unit: Veterinary Clinical Sciences, Department of
Publisher: American Society for Pharmacology and Experimental Therapeutics; Bethesda, MD
Identifiers: 99900547464101842
Language: English
Resource Type: Journal article