Journal article
Vitamin B6: A Long Known Compound of Surprising Complexity
Molecules (Basel, Switzerland), Vol.14(1), pp.329-351
01/2009
Handle:
https://hdl.handle.net/2376/111196
PMCID: PMC6253932
PMID: 19145213
Abstract
In recent years vitamin B6 has become a focus of research describing the compound’s critical function in cellular metabolism and stress response. For many years the sole function of vitamin B6 was considered to be that of an enzymatic cofactor. However, recently it became clear that it is also a potent antioxidant that effectively quenches reactive oxygen species and is thus of high importance for cellular well-being. In view of the recent findings, the current review takes a look back and summarizes the discovery of vitamin B6 and the elucidation of its structure and biosynthetic pathways. It provides a detailed overview on vitamin B6 both as a cofactor and a protective compound. Besides these general characteristics of the vitamin, the review also outlines the current literature on vitamin B6 derivatives and elaborates on recent findings that provide new insights into transport and catabolism of the compound and on its impact on human health.
Metrics
12 Record Views
Details
- Title
- Vitamin B6: A Long Known Compound of Surprising Complexity
- Creators
- Sutton Mooney - School of Biological Sciences, Washington State University, Pullman, WA, USA; E-mailJan-Erik Leuendorf - Angewandte Genetik, Freie Universität Berlin, 14195 Berlin, Germany E-mailChristopher Hendrickson - School of Biological Sciences, Washington State University, Pullman, WA, USA; E-mailHanjo Hellmann - School of Biological Sciences, Washington State University, Pullman, WA, USA; E-mail
- Publication Details
- Molecules (Basel, Switzerland), Vol.14(1), pp.329-351
- Academic Unit
- Biological Sciences, School of
- Publisher
- Molecular Diversity Preservation International
- Identifiers
- 99900546924901842
- Language
- English
- Resource Type
- Journal article